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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ11
All Species:
25.45
Human Site:
S363
Identified Species:
62.22
UniProt:
Q14654
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14654
NP_000516
390
43541
S363
L
E
A
L
T
L
A
S
A
R
G
P
L
R
K
Chimpanzee
Pan troglodytes
XP_521849
390
43540
S363
L
E
A
L
T
L
A
S
A
R
G
P
L
R
K
Rhesus Macaque
Macaca mulatta
XP_001089155
390
43552
S363
L
E
A
L
T
L
A
S
A
R
G
P
L
R
K
Dog
Lupus familis
XP_542519
390
43410
S363
L
D
A
L
T
L
A
S
A
R
G
P
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61743
390
43543
S363
L
D
A
L
T
L
A
S
S
R
G
P
L
R
K
Rat
Rattus norvegicus
P70673
390
43589
S363
L
D
A
L
T
L
A
S
S
R
G
P
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509905
401
44343
S375
L
D
T
L
P
L
T
S
P
K
S
Q
L
R
K
Chicken
Gallus gallus
Q90854
492
55398
A367
S
S
P
L
I
A
P
A
V
S
N
S
K
E
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034916
381
42766
E355
L
E
E
A
G
G
M
E
R
F
K
L
Q
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
V449
Q
S
S
S
N
S
P
V
F
S
N
N
H
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
97.4
N.A.
96.4
96.1
N.A.
87
37.2
N.A.
70.2
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
100
99.7
99.4
98.4
N.A.
97.6
97.6
N.A.
92.7
55.6
N.A.
81.5
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
46.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
60
20
N.A.
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
10
0
10
60
10
40
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
40
10
0
0
0
0
10
0
0
0
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
60
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
0
10
0
80
% K
% Leu:
80
0
0
80
0
70
0
0
0
0
0
10
70
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
20
10
0
0
0
% N
% Pro:
0
0
10
0
10
0
20
0
10
0
0
60
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
60
0
0
0
70
10
% R
% Ser:
10
20
10
10
0
10
0
70
20
20
10
10
0
10
0
% S
% Thr:
0
0
10
0
60
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _